Project number: VPP-COVID-2020 / 1-0014

Type: National research program “Mitigation of Covid-19 effects”

Duration of the project: 01.07.2020 - 31.12.2020

Project manager: Latvian Biomedical Research and Study Center (BMC), Dr. biol. Kaspars Tārs

Cooperation partners: Latvian Institute of Organic Synthesis; Institute of Solid State Physics, University of Latvia (ISSP UL); Riga Technical University; University of Latvia

Project manager from ISSPUL: Gatis Mozolevskis

Total funding: EUR 500 000

ISSP UL funding: EUR 48 809

Project summary:

To develop new vaccine candidates and small molecule drug leader compounds against coronaviruses, especially COVID-19 and its complications. The goal of the project is development of a vaccine candidate, development of new small molecule leader compounds and re-profiling of existing drugs to reduce COVID-19 complications.

Tasks of ISSP UL:

In collaboration with the BMC, to develop lung-on-chip device, which will allow to study of SARS-CoV-2 infection processes. The device will be fabricated from PDMS and protocols will be developed to fabricate the devices from alternative materials.