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ISSP UL scientific workshop (16.10.2019) 4D Biofabrication

Fig. 1. Fabrication of self-folding hydrogel-based (cell-laden) tubes via 4D bioprinting: a) printing of mathacrylated alginate or hyaluronic acid solutions; b) crosslinking of the printed films with green light (530 nm) and mild drying; c) instant folding into tubes upon immersion of the crosslinked films in water, PBS, or cell culture media; d) examples of the fabricated self-folding tubes (from right to left): schematic illustrations and representative microscope images of single tubes with/without printed cells formed through the described 4D printing process; photograph of a glass vial containing a large number of self-folded tubes, indicating on the possibility of their large-scale fabrication.

On October 16 at 13:00 at the conference room on the 2nd floor of the ISSP UL, Kengaraga street 8, Indra Apsīte (University of Bayreuth, Professorship of Biofabrication, Germany) will give a talk entitled “4D Biofabrication”.

We utilize biologically inspired strategies to develop new functional and active 3D (bio-)materials based on actuating polymers for soft robotics, smart textiles, soft electronics, energy storage materials, and tissue engineering as well as for a variety of other scientific and industrial applications. Particular focus is processing of stimuli-responsive, shape memory polymers and hydrogels. To process various polymers we use fused filament printing, extrusion printing of hydrogels, ink-jet printing, electrospinning, meltelectrowring as well as stereolithography. Our particular focus is 4D biofabrication, which is fabrication of cellular structures by shape-transformation of 3D objects. We pioneered fabrication of 4D biofabrication using most important biodegradable polymers, which are widely used in tissue engineering, such as gelatin, alginate and hyaluronic acid.

Baltijas-Vācijas Augstskolu biroja projektu finansiāli atbalsta Vācijas Akadēmiskās apmaiņas dienests (DAAD) no Vācijas Ārlietu ministrijas piešķirtajiem līdzekļiem. 

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